Throughout most of history the perception of a nurse has been interpreted as a bedside maid serving the doctor under whom she worked. However, nurses have been defining, implementing, and initiating evidence-based practices for over one hundred years (What's, 2011). The application of evidence-based nursing practice is concomitant with the effect on improving patient outcomes (Davis, 2016). Evidence-based practice has evolved into the need for healthcare teams working together to continually seek the best outcomes for patients treated as a unit (Kerr,2007). Furthermore, the trinitarian relationship that exists between research, evidence-based practice and behind-the-scenes quality control work to produce a decrease in errors with patients. Nurses should understand the significance of this revolution so they can aid in its progression. Evidence-based practice is defined as evaluating research, clinical practices, and other relevant information, then using the findings to promote patient-centered care (Evidence, 2016). While this term, “evidence-based practice,” may be new, the implementation of this idea has been widely present in nursing. The results of evidence-based practice have been discovered since the mid-nineteenth century. However, the term was first considered common parlance in the 1980s, then became common parlance in 1922, when the Journal of the American Medical Association published its article, "Evidence-Based Medicine Working Group," which explained the importance of this phenomenon in medical training and practice (What's, 2011). By renewing this ancient practice, nurses are able to multiply the quality and safety in patient care. This is done by the nurse detecting the presenting problem, determining the appropriate treatments needed based on knowledge, implementing appropriate interventions, then examining the conclusion of the interventions as to their success (Scott & McSherry, 2016). Ultimate need For patients to receive the best care, all three factors must be present and play an active role. These three factors are quality improvement, evidence-based practice and research. The combination of these elements strengthens quality in an environment that supports skilled and educated practice, while uncovering excellence in the delivery of nursing practices (Conner, 2016). The domino effect of this Trinitarian relationship is a reduction in harmful patient errors resulting in increased patient safety, so there may never be a perfect environment, the drive for perfection must always be present (Hughes,